Susanna M Saario : rechercher sur Z-Library

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1

4-Phenylbutanoyl-2(S)-acylpyrrolidines and 4-phenylbutanoyl-l-prolyl-2(S)-acylpyrrolidines as prolyl oligopeptidase inhibitors

Erik A.A Wallén, Johannes A.M Christiaans, Susanna M Saario, Markus M Forsberg, Jarkko I Venäläinen, Hanna M Paso, Pekka T Männistö, Jukka Gynther

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 154 KB

english, 2002

2

Fatty Acid Amide Hydrolase Inhibitors from Virtual Screening of the Endocannabinoid System

Saario, Susanna M., Poso, Antti, Juvonen, Risto O., Järvinen, Tomi, Salo-Ahen, Outi M. H.

Journal:

Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 259 KB

english, 2006

3

Monoglyceride Lipase as an Enzyme Hydrolyzing 2-Arachidonoylglycerol

Susanna M. Saario, Jarmo T. Laitinen

Journal:

Chemistry & Biodiversity

Année:

2007

Langue:

english

Fichier:

PDF, 293 KB

english, 2007

4

Screening of Various Hormone-Sensitive Lipase Inhibitors as Endocannabinoid-Hydrolyzing Enzyme Inhibitors

Anna Minkkilä, Juha R. Savinainen, Heikki Käsnänen, Henri Xhaard, Tapio Nevalainen, Jarmo T. Laitinen, Antti Poso, Jukka Leppänen, Susanna M. Saario

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 700 KB

english, 2009

5

3-Heterocycle-Phenyl N-Alkylcarbamates as FAAH Inhibitors: Design, Synthesis and 3D-QSAR Studies

Heikki Käsnänen, Mikko J. Myllymäki, Anna Minkkilä, Antti O. Kataja, Susanna M. Saario, Tapio Nevalainen, Ari M. P. Koskinen, Antti Poso

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 940 KB

english, 2010

6

Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide

Teija Parkkari, Juha R. Savinainen, Katri H. Raitio, Susanna M. Saario, Laura Matilainen, Tuomas Sirviö, Jarmo T. Laitinen, Tapio Nevalainen, Riku Niemi, Tomi Järvinen

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 159 KB

english, 2006

7

Characterization of the Sulfhydryl-Sensitive Site in the Enzyme Responsible for Hydrolysis of 2- Arachidonoyl-Glycerol in Rat Cerebellar Membranes

Susanna M. Saario, Outi M.H. Salo, Tapio Nevalainen, Antti Poso, Jarmo T. Laitinen, Tomi Järvinen, Riku Niemi

Journal:

Chemistry & Biology

Année:

2005

Langue:

english

Fichier:

PDF, 301 KB

english, 2005

8

URB754 Has No Effect on the Hydrolysis or Signaling Capacity of 2-AG in the Rat Brain

Susanna M. Saario, Ville Palomäki, Marko Lehtonen, Tapio Nevalainen, Tomi Järvinen, Jarmo T. Laitinen

Journal:

Chemistry & Biology

Année:

2006

Langue:

english

Fichier:

PDF, 142 KB

english, 2006

9

α-Methylated derivatives of 2-arachidonoyl glycerol: Synthesis, CB1 receptor activity, and enzymatic stability

Teija Parkkari, Mikko Myllymäki, Juha R. Savinainen, Susanna M. Saario, Joel A. Castillo-Meléndez, Jarmo T. Laitinen, Tapio Nevalainen, Ari M.P. Koskinen, Tomi Järvinen

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 114 KB

english, 2006

10

The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors

Anna Minkkilä, Mikko J. Myllymäki, Susanna M. Saario, Joel A. Castillo-Melendez, Ari M.P. Koskinen, Christopher J. Fowler, Jukka Leppänen, Tapio Nevalainen

Journal:

European Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 611 KB

english, 2009

11

Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields

Mikko J. Myllymäki, Heikki Käsnänen, Antti O. Kataja, Maija Lahtela-Kakkonen, Susanna M. Saario, Antti Poso, Ari M.P. Koskinen

Journal:

European Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 870 KB

english, 2009

12

Therapeutic Potential of Endocannabinoid-Hydrolysing Enzyme Inhibitors

Susanna M. Saario, Jarmo T. Laitinen

Journal:

Basic & Clinical Pharmacology & Toxicology

Année:

2007

Langue:

english

Fichier:

PDF, 136 KB

english, 2007

13

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors

Juha R Savinainen, Susanna M Saario, Riku Niemi, Tomi Järvinen, Jarmo T Laitinen

Journal:

British Journal of Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 200 KB

english, 2003

14

Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes

Susanna M Saario, Juha R Savinainen, Jarmo T Laitinen, Tomi Järvinen, Riku Niemi

Journal:

Biochemical Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 143 KB

english, 2004

15

Discovery of Boronic Acids as Novel and Potent Inhibitors of Fatty Acid Amide Hydrolase

Minkkilä, Anna, Saario, Susanna M., Käsnänen, Heikki, Leppänen, Jukka, Poso, Antti, Nevalainen, Tapio

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 129 KB

english, 2008

16

Allelopathic Potential of Lingonberry ( Vaccinium vitis-idaea L.) Litter for Weed Control

Saario, Meeri, Koivusalo, Susanna, Laakso, Into, Autio, Janne

Journal:

Biological Agriculture & Horticulture

Année:

2002

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2002

17

Chiral 1,3,4-Oxadiazol-2-ones as Highly Selective FAAH Inhibitors

Patel, Jayendra Z., Parkkari, Teija, Laitinen, Tuomo, Kaczor, Agnieszka A., Saario, Susanna M., Savinainen, Juha R., Navia-Paldanius, Dina, Cipriano, Mariateresa, Leppänen, Jukka, Koshevoy, Igor O., P

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2013

18

1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling

Käsnänen, Heikki, Minkkilä, Anna, Taupila, Susanna, Patel, Jayendra Z., Parkkari, Teija, Lahtela-Kakkonen, Maija, Saario, Susanna M., Nevalainen, Tapio, Poso, Antti

Journal:

European Journal of Pharmaceutical Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2013

19

Design, Synthesis, and In Vitro Evaluation of Carbamate Derivatives of 2-Benzoxazolyl- and 2-Benzothiazolyl-(3-hydroxyphenyl)-methanones as Novel Fatty Acid Amide Hydrolase Inhibitors.

Myllymäki, Mikko J., Saario, Susanna M., Kataja, Antti O., Castillo-Melendez, Joel A., Nevalainen, Tapio, Juvonen, Risto O., Järvinen, Tomi, Koskinen, Ari M. P.

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 6 KB

english, 2007

20

Design, Synthesis, and In Vitro Evaluation of Carbamate Derivatives of 2-Benzoxazolyl- and 2-Benzothiazolyl-(3-hydroxyphenyl)-methanones as Novel Fatty Acid Amide Hydrolase Inhibitors

Myllymäki, Mikko J., Saario, Susanna M., Kataja, Antti O., Castillo-Melendez, Joel A., Nevalainen, Tapio, Juvonen, Risto O., Järvinen, Tomi, Koskinen, Ari M. P.

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 109 KB

english, 2007

21

Discovery and Development of Endocannabinoid-Hydrolyzing Enzyme Inhibitors

Minkkila, Anna, M. Saario, Susanna, Nevalainen, Tapio

Journal:

Current Topics in Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 985 KB

english, 2010